apex scientific

Sapphire Biomolecular Imaging

The Biomolecular Imager systems from Azure Biosystems provide laboratories with advanced versatility for a wide range of imaging applications. Supporting Phosphor Imaging, In vivo Imaging, Chemiluminescent Imaging, Western Blots, Gel Imaging, Organ and Tumor Imaging, and Tissue Imaging, these instruments deliver exceptional sensitivity, resolution, and flexibility. With customizable optical modules, broad detection capabilities, and innovative features designed for both research and clinical workflows, the range includes multiple models that adapt to evolving experimental requirements.

Whether you require high-resolution imaging, live-animal analysis, or phosphor screen scanning, Azure Biosystems solutions combine precision with adaptability. Explore our full range and see which model best suits your lab needs.

 

Brochure
Enquire
Biomolecular Imager
Biomolecular Imager

The Biomolecular Imaging range from Azure Biosystems delivers flexibility and sensitivity for advanced laboratory imaging. These systems support Phosphor Imaging, In vivo Imaging, Chemiluminescent Imaging, Western Blots, Gel Imaging, Organ and Tumor Imaging, and Tissue Imaging, and therefore adapt easily to diverse experimental workflows.

 

Sapphire FL

The Sapphire FL includes customizable optical modules with exchangeable lasers and filters. This design enables precise excitation across the UV to NIR spectrum. It offers 5–1000 μm resolution, extended dynamic range, and a software-controlled focal plane. As a result, researchers can detect both subtle and high-intensity signals with accuracy. Furthermore, the system supports live-animal imaging through multiple anesthesia ports. In addition, an optional chemiluminescent module provides femtogram sensitivity for protein detection.

 

Sapphire FL+

The Sapphire FL+ builds on these features and adds support for Phosphor Imaging of large storage screens up to 20 × 40 cm. With laser excitation and PMT detection, it delivers outstanding image quality and dynamic range. Like the Sapphire FL, it accommodates Western blots, gels, tissues, and organs. Moreover, it maintains high resolution and adjustable focus across all sample types, ensuring consistent results.

 

Adaptable Solutions for Research

Both models provide flexible imaging for fluorescence, chemiluminescence, and phosphor assays. Consequently, they ensure reliable performance for protein studies, molecular biology, and small-animal research. Because of their modular design, laboratories can select the best configuration today while remaining adaptable for future applications.

Explore our full range and see which model best suits your lab needs.

ModelSapphire FLSapphire FL+
Detection modesFluorescence, phosphor imaging, densitometry, and chemiluminescence*Fluorescence, phosphor imaging, densitometry, and chemiluminescence*
DetectorsConfocal scanning with lasers and PMT or APD detectorsConfocal scanning with lasers and PMT or APD detectors
Pixel size5, 10, 20, 25, 50, 75, 100, 150, 170, 200, 500, 1000 μm5, 10, 20, 25, 50, 75, 100, 150, 170, 200, 500, 1000 μm
Supported wavelength range375 – 900 nm375 – 900 nm
Excitation range375 – 850 nm375 – 850 nm
Emission range380 – 900 nm380 – 900 nm
Maximum field of view (FOV):25 cm x 25 cm46 cm x 25 cm
Z-plane focal range7 mm; minimum delta 0.01mm, from -1 mm below the glass to 6 mm above the glass7 mm; minimum delta 0.01mm, from -1 mm below the glass to 6 mm above the glass
Standard optical modulesSolid-state laser diodes emitting at 375, 450, 488, 532, 638, 658, 685, 730, and 784 nm. Phosphor Standard Optical Module available.Solid-state laser diodes emitting at 375, 450, 488, 532, 638, 658, 685, 730, and 784 nm. Phosphor Standard Optical Module available.
Custom Optical ModulesCustom lasers and filters are available upon request to provide exceptional research flexibility.Custom lasers and filters are available upon request to provide exceptional research flexibility.
Wide dynamic range24-bit24-bit
Clearance from platen to lid4 cm5 cm
Animal imagingYes, with 5 built-in anesthesia ports compatible with standard small animal anesthesia tubing–
Unit dimensions (W x H x D)63.0 cm x 39.9 cm x 59.3 cm / 24.8” x 15.7” x 23.3″96.8 x 66 x 40.7 cm (38.1 x 26 x 16 in)
Weight43.5 kg / 95.9 lbs71 kg / 156.5 lbs
Power requirements100 – 240 VAC ± 10%, 50/60 Hz100 – 240 VAC ± 10%, 50/60 Hz
Connection to computerFast LAN (Ethernet) cableFast LAN (Ethernet) cable
CertificationsCE, cTUVus, CB schemeCE, RoHS, cTUVus, CSA, CB scheme
SKUDescription
IS4000Sapphire FL Biomolecular Imager – Laser based scanning system supporting 375nm excitation to 900nm emission. Adjustable Z focus, 5-1000 micron resolution, 25cm x 25cm FOV. (This item must be quoted with IS2011 or IS2012.)

 

Sapphire Computer

SKUDescription
IS2011Compact Workstation with Embedded Monitor for Sapphire FL – Compact workstation with a built-in monitor, running Windows and configured with Sapphire Capture Software for operating the Sapphire FL Biomolecular Imager. Includes power cable, embedded keyboard and touchpad.
IS2012Desktop Workstation with External High-Resolution Monitor for Sapphire FL – Premium high-performance desktop workstation with a large 27″ high-resolution 4K monitor, running Windows and configured with Sapphire Capture Software for operating the Sapphire FL Biomolecular Imager. Includes power and monitor cables, external keyboard and mouse.

 

Standard Modules

SKUDescription
IS4030375 Standard Optical Module – Includes 375 nm laser and 452/45 filter
IS4031450 Standard Optical Module – Includes 450 nm laser and 494/34 filter
IS4001488 Standard Optical Module – Includes 488 nm laser and 513/17 filter
IS4032488 (YFP) Standard Optical Module – Includes 488 nm laser and 534/20 filter
IS4002532 Standard Optical Module – Includes 532 nm laser and 572/28 filter
IS4033532 (Propidium) Standard Optical Module – Includes 532 nm laser and 624/40 filter
IS4003638 Standard Optical Module – Includes 638 nm laser and 676/37 filter
IS4057658 Standard Optical Module – Includes 658 nm laser and 710/40 filter
IS4004685 Standard Optical Module – Includes 685 nm laser and 720/24 filter
IS4066730 Standard Optical Module – Includes 730 nm laser and 809/81 filter
IS4005784 Standard Optical Module – Includes 784 nm laser and 829/62 filter
IS4006Phosphor Imaging Standard Optical Module – Adds Phosphor Imaging to Sapphire FL

 

Laser Options

SKUDescription
IS4023Sapphire FL 375 nm Laser – 375 nm laser module (not including emission filter)
IS4024Sapphire FL 450 nm Laser – 450 nm laser module (not including emission filter)
IS4025Sapphire FL 488 nm Laser – 488 nm laser module (not including emission filter)
IS4055Sapphire FL 488 nm (YFP) Laser – 488 nm (YFP) laser module (not including emission filter)
IS4026Sapphire FL 532 nm Laser – 532 nm laser module (not including emission filter)
IS4027Sapphire FL 638 nm Laser – 638 nm laser module (not including emission filter)
IS4059Sapphire FL 658 nm Laser – 658 nm laser module (not including emission filter)
IS4028Sapphire FL 685 nm Laser – 685 nm laser module (not including emission filter)
IS4067Sapphire FL 730 nm Laser – 730 nm laser module (not including emission filter)
IS4029Sapphire FL 784 nm Laser – 784 nm laser module (not including emission filter)

 

Filter Options

SKUDescription
IS4056Sapphire FL 424/SP Filter – 424/SP nm filter
IS4008Sapphire FL 452 Filter – 452/45 nm filter
IS4011Sapphire FL 494 Filter – 494/34 nm filter
IS4012Sapphire FL 513 Filter – 513/17 nm filter
IS4010Sapphire FL 534 Filter – 534/20 nm filter
IS4049Sapphire FL 572 Filter – 572/28 nm filter
IS4013Sapphire FL 624 Filter – 624/40 nm filter
IS4009Sapphire FL 676 Filter – 676/37 nm filter
IS4058Sapphire FL 710 Filter – 710/40 nm filter
IS4046Sapphire FL 720 Filter – 720/24 nm filter
IS4068Sapphire FL 809 Filter – 809/81 nm filter
IS4047Sapphire FL 829 Filter – 829/62 nm filter

 

Chemi Modules

SKUDescription
IS4060Sapphire FL Advanced Chemiluminescence Module – Adds Advanced Chemiluminescence Module to Sapphire FL (AZI300-01)
IS4007Sapphire FL Chemiluminescence Module – Adds Basic Chemiluminescence Module to Sapphire FL (CS1000)
IS4052Sapphire FL Ethernet Connection Kit – Ethernet connection kits for the Basic Chemiluminescence Module, contains 7 Foot Cat6 (UTP) Ethernet Cable and 4 port Netgear Ethernet switch

 

Sapphire Accessories

SKUDescription
IS1010Sapphire Mat – Designed for flattening membranes against the glass surface
IS2018Azure DensitoMetrics – Sapphire densitometry package for Sapphire Biomolecular Imager with a green channel (520 nm laser).
IS4053Sapphire FL Slide Holder – Fixture designed to hold up to 15 standard microscope slides for use with the Sapphire FL.
IS4054Sapphire FL Plate Holder – Fixture designed to hold up to four standard 96-well plates with optically clear bottoms for use with the Sapphire FL.
IS4069Azure Test Target (Black) – Azure Test Target with black background and transparent areas around bands and logo

 

Anesthesia Accessories

SKUDescription
IS4050Anesthesia Nose Cone – Set of five 7mm anesthesia nose cones for a tight fit with laboratory mice. For use with Anesthesia Tubing (IS4051).
IS4051Anesthesia Tubing – 18 inches of tubing with luer fittings for use with 7mm Anesthesia Nose Cones (IS4050). Compatible with low-flow electronic vaporizers and the Sapphire FL.

 

Analysis Software for 1D

SKUDescription
AC1078AzureSpot Pro – Analysis of 1D gels and Western blots, band analysis, array analysis, colony counting. PC and Mac compatible. Electronic License with 4 computer installations.
AC1132AzureSpot Pro 20 – Analysis of 1D gels and Western blots, band analysis, array analysis, colony counting. PC and Mac compatible. Electronic License with 20 computer installations.

 

Analysis Software for 2D

SKUDescription
IS1013SameSpots 2D Analysis Software – SameSpots software package for 2D analysis of both DIGE and single stains, is simple to use and gives you fast, objective results for differential expression of intact proteins using 2-D gels. Electronic License with 1 computer installation.
IS1014SpotMap Analysis Software – SpotMap software package is unique and easy-to-use software specifically designed for analysis of HCP (host cell protein) coverage for biologic product characterisation, process development/optimisation and HCP antibody assay and impurity profiling. Electronic License with 1 computer installation.

 

Analysis Software for GxP

SKUDescription
AC1077AzureSpot Pro GxP – Software package for analysis of 1D gels and blots. Assists compliance with 21 CFR Part 11. Includes IQ OQ for the software. Electronic License with 1 computer installation.
AC1075SpotMap GxP – SpotMap software package unique and easy-to-use software specifically designed for analysis of HCP (host cell protein) coverage for biologic product characterization, process development/optimization and HCP antibody assay & impurity profiling. Assists compliance with 21CFR Part11. Includes IQ OQ. Electronic License with 1 computer installation.

 

Sapphire IQOQ

SKUDescription
IS4020Sapphire FL IQOQ Documentation – IQOQ documentation for Sapphire FL Biomolecular Imager and associated fluorescent optical modules. Includes Procedure, Checklist and Logbook, Azure Test Targets, and Certificates. Excludes service.
IS4021Sapphire FL IQOQ Service – Service for performing IQOQ procedure for Sapphire FL Biomolecular Imager

 

Warranty

SKUDescription
IS4042Additional 1-Year Warranty Sapphire FL – International – Extends standard warranty by 1 year for the Sapphire FL imager

Product Datasheet – FL / FL+

Biomolecular Imager Applications and Publications

Webinar – Sapphire FL Biomolecular Imager

Product Enquiry

"*" indicates required fields

This field is hidden when viewing the form
First Name*
Last Name*
Consent*

Related products