HetaSep by StemCell Technologies is a specialized erythrocyte aggregation agent designed for fast and efficient separation of nucleated cells from red blood cells (RBCs) in whole blood. Now available in South Africa through Apex Scientific, this reagent streamlines laboratory workflows by enabling RBCs to rapidly aggregate and settle without complex equipment or harsh lysis steps.
Rapid and Gentle Cell Separation
HetaSep promotes erythrocyte aggregation, causing RBCs to settle quickly after a brief incubation or low-speed centrifugation. Scientists can then extract the upper layer containing white blood cells and other nucleated cells. This approach preserves cell integrity and supports high sample quality for downstream applications.
High Recovery of Target Cells
HetaSep achieves approximately 95–99% RBC depletion while preserving immune cells and hematopoietic stem cells. Its 6% w/v hetastarch formulation enhances RBC sedimentation without damaging nucleated cells. This ensures high viability and recovery for research involving leukocytes, granulocytes, and other cell populations.
Applications Across Research Fields
Ideal for immunology, stem cell biology, and blood processing, HetaSep supports negative selection workflows by enriching nucleated cells from human cord or whole blood samples. It integrates well with other tools like EasySep™ kits and is suitable for use before flow cytometry, culture, or magnetic separation.
Local Supply and Support
Apex Scientific offers HetaSep as part of our advanced laboratory equipment range in South Africa, with full technical support. Our team helps local labs implement efficient, reproducible cell isolation protocols. Visit the Apex Scientific Insights page to learn more about how HetaSep can enhance your research.