The human umbilical vein endothelial cells (HUVECs) from StemCell Technologies are ethically sourced, ready-to-use primary cells designed to streamline laboratory assays. Available in South Africa through Apex Scientific, these cells come from a single healthy donor’s umbilical vein using a collagenase digestion process. They grow in xeno-free EC-Cult™-XF medium and freeze at early passage 2 in CryoStor® CS10, a cGMP-grade cryopreservation medium. Each vial contains over 500,000 viable cells, providing consistent and reproducible results.
High Viability and Expansion
HUVECs deliver exceptional post-thaw viability, exceeding 90%. When cultured in complete EC-Cult™-XF medium, they can double more than 16 times, allowing large-scale experiments from one vial. Apex Scientific, a leading supplier of laboratory equipment in South Africa, ensures every batch arrives in optimal condition for reliable use.
Stable Phenotype and Functionality
These cells maintain strong endothelial marker expression (CD31 and CD144) across multiple passages. They also demonstrate key vascular functions, such as tube formation in vitro and acetylated LDL uptake, confirming their physiological relevance in research applications.
Research Uses
Scientists use the human umbilical vein to study inflammation, angiogenesis, oxidative stress, hypoxia, and blood vessel formation. They are also valuable for drug screening, cardiovascular research, and regenerative medicine. Sourcing HUVECs through Apex Scientific ensures South African labs have dependable access to this critical cell model.
Ethical and Quality Standards
All donors provide informed consent under IRB-approved protocols. Screening confirms they are free from HIV-1, HIV-2, hepatitis B, and hepatitis C. Flow cytometry verifies ≥95% endothelial purity with ≤5% non-endothelial cells. Optional donor data, HLA typing, and CMV status are available on request.
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