The human T cell activation is a key process in immunology research and cell therapy development. Apex Scientific supplies the ImmunoCult™ Human CD3/CD28 T Cell Activator from StemCell Technologies to laboratories across South Africa. This reagent stimulates and expands T cells without magnetic beads, feeder cells, or antigens. Soluble antibody complexes bind and cross-link CD3 and CD28 receptors on T cells, delivering activation signals without harsh methods that could damage cell health.
After activation, researchers can expand T cells in ImmunoCult™-XF T Cell Expansion Medium or other suitable culture media. The activator works seamlessly with a variety of laboratory workflows. For example, it can be used with the Agilent Seahorse XF Analyzer to measure activation responses in real time.
Key Advantages
- Bead-Free Activation: Robust human T cell activation without magnetic beads, feeder layers, or added antigens, simplifying workflows and reducing variability.
- High Viability and Yield: Gentle stimulation preserves T cell health and supports strong expansion of CD4+ and CD8+ cells.
- Ready-to-Use Stability: A sterile, soluble antibody complex that integrates easily with existing laboratory equipment and protocols.
Applications
This activator is ideal for research on T cell function, immune responses, and cell therapy development. Researchers use it for rapid human T cell activation, cellular expansion, functional assays, and immunophenotyping. It is also valuable in metabolic and functional studies, such as real-time activation measurements with the Seahorse XF Analyzer.
This product is for research use only. Apex Scientific delivers it with expert support and a full range of laboratory equipment for immunology research in South Africa. For protocols and best practices, visit our Insights page.
