Microelectrode Analyzer (MEA) – Maestro Edge

Microelectrode Analyzer (MEA) – Maestro Edge from Axion Biosystems is a state-of-the-art multiwell system designed for versatile multimodal applications with 6-, 24-, and 96-well throughput. This innovative Microelectrode Analyzer (MEA) noninvasively evaluates cellular function, making it an essential tool for researchers.

Whether you’re monitoring the intricate electrical activity of neurons and cardiomyocytes or tracking the growth and death of cancer cells, the Maestro Edge delivers high-quality functional data that accelerates your research. Explore our range of laboratory equipment at Apex Scientific and learn more about how the Maestro Edge can enhance your studies through our Insights page.

The Maestro Edge Microelectrode Analyzer (MEA) from Axion Biosystems is a cutting-edge tool designed to measure cellular activity in real-time, label-free. This advanced system is pivotal for assessing key parameters of neural network activity, cardiac functionality, and cell growth, death, and attachment, making it an essential addition to your laboratory equipment.

Precisely Control the Cell Environment

Cells thrive in a controlled environment. The maestro edge features a smart environmental chamber that precisely regulates temperature and CO₂ levels while minimizing electrical noise and mechanical vibrations. This ensures optimal conditions for your experiments.

 

Connect to Your Network

With the Neural and Cardiac modules, the MEA enables 384 simultaneous live recordings from your cells. Understand life’s circuitry in real-time and label-free using 6- or 24-well plates, enhancing your research capabilities.

 

Continuous Cell Monitoring

For those requiring detailed insights, the Impedance module allows 96 simultaneous live recordings. Monitor cell proliferation, morphology, and viability continuously in real-time, providing a comprehensive view of cellular dynamics.

 

See Your Cells

Visualizing your cells is crucial. The Maestro Edge’s patented CytoView™ transparent circuit technology allows for easy observation and assay multiplexing, bridging the gap between data and visual confirmation.

 

Control Cellular Activity

Recreate specific patterns of cellular activity using electrical stimulation or light pulses with the Lumos optical stimulation system. This feature empowers researchers to manipulate cellular responses effectively.

 

Maestro Edge overview

Electrical activity can give important context to your research. Detailed functional characterization is critical for understanding disease mechanisms, but many researchers avoid it because the techniques can be laborious. Electrophysiology doesn’t have to be difficult. The Maestro MEA platform makes it easy to perform complex electrophysiological experiments and gain deep insights into the function of cells. But the Maestro Edge isn’t just an MEA system — it also features sensitive impedance-measuring capabilities to monitor the kinetics of cellular growth, death, and signaling in real time. ​

Since launching our first multiwell plate-based Maestro MEA system more than a decade ago, it has become an indispensable tool in academic, biotech, and pharma labs around the world.

Customize your MEA

Customize your MEA

Start Your Assay with the Push of a Button

Experience ease of use with the one-button setup that automatically adjusts temperature and CO₂ levels upon plate docking. An integrated plate barcode scanner logs plate usage for effortless experiment tracking.

Impedance Cell Analyzer - Maestro Z

Multiplex your assay: Maestro + Omni

Platform cross-compatibility lets you view live-cell imaging alongside real-time, functional data to enhance your analysis. Monitor electrode coverage and cell morphology to ensure consistent, high-quality results across experiments. Experience no-hassle tracking—the Axion Portal automatically links all relevant data via barcode for easy access and streamlined data management.

Monitor Kinetics Anywhere

With the Impedance module, you can track changes in cell proliferation, viability, and cell death remotely via your smartphone. Stay connected to your research without being tied to the lab.

Accessories


For more information and options, look at our article, Micro Electrode Array Analyzers for Advanced Live Cell Analysis in South Africa on our Insights page, where you will find detailed articles that assist you in understanding various products and applications.

FeaturesMaestro ProMaestro EdgeMaestro Volt
Throughput (well format)6, 24, 48, 96, 384*
*Well format available in impedance only
6, 24, 96*
*Well format available in impedance only
6
MEA Mode
MEA Viability
Impedance Mode
Environmental Control
Automation API
StimulationElectrical & OpticalElectrical & OpticalElectrical
Omni Compatible
SKUDescription
MAESTRO384EDGEMaestro Edge, 384-channel electrode-based assay system for MEA and impedance applications. Includes BioCore v4 chip technology, stimulation, recording and data acquisition system, automated temperature and CO2 control, desktop computer, and monitor. Accommodates Axion BioSystems’ 6 and 24-well MEA plates as well as 96-well CytoView-Z plates (SLAS compliant). 1 year warranty is included.

 

Software and Modules

SKUDescription
CARDIO-EDGECardiac Module for Maestro Edge, Cardiac data acquisition and analysis module with AxIS Navigator Software. Includes field potentials, LEAP assay, contractility, propagation, electrical stimulation, and optical stimulation (using Lumos, sold separately).
NEURO-EDGENeural Module for Maestro Edge, Neural data acquisition and analysis module with AxIS Navigator Software. Includes neural spikes, field potentials, network activity, electrical stimulation, and optical stimulation (using Lumos, sold separately).
MEA-VIA-EDGEMEA Viability Module for Maestro Edge, Viability extension for the Cardiac and/or Neural Modules with AxIS Navigator Software. Enables acquisition and analysis of impedance-based viability data from CytoView MEA plates.
MEA-AUTO-EDGEMEA Automation Module for Maestro Edge, AxIS Navigator application programming interface (API) for interfacing with liquid handling platforms or other systems to automate MEA experiments. Includes functions for data acquisition and analysis.
IMP-EDGEImpedance Automation Module for Maestro Z or Maestro Edge, AxIS Z application programming interface (API) for interfacing with liquid handling platforms or other systems to automate impedance experiments. Includes functions for experiment setup and data acquisition.
AXIS-ANALYSIS-BASEAxIS Analysis license for Maestro Pro, Edge, and Volt, analysis extension for the Neural Module with AxIS Navigator software. Includes multi-file support, streamlined workflow, new visualizations (i.e. box and whisker plots, heatmap, scatter plots, radar plots) and reporting functionality. Base license includes 2 seats.
AXIS-ANALYSIS-SEATAdditional seat for AxIS Analysis license. Available only with existing base AxIS Analysis license.

 

Compatible Plates

SKUDescription
M384-tMEA-6BCytoView MEA 6-Black plate, 64 microelectrodes per well, black polystyrene walls with a transparent SU-8 bottom, case of 5 plates
M384-tMEA-6WCytoView MEA 6-White plate, 64 microelectrodes per well, white polystyrene walls with a transparent SU-8 bottom, case of 5 plates
M384-BIO-24BioCircuit MEA 24 plate, 16 microelectrodes per well including one large stimulation electrode per well, clear polystyrene walls with an opaque bottom, includes on-plate spotting guides. Box of 5 plates
M384-tMEA-24OPTLumos MEA 24 plate, 16 microelectrodes per well including one large stimulation electrode per well, white polystyrene walls with a transparent SU-8 bottom, includes the Lumos lid, box of 5 plates
M384-tMEA-24WCytoView MEA 24-White plate, 16 micro-electrodes per well including one large stimulation electrode per well, white polystyrene walls with a transparent SU-8 bottom, box of 5 plates
OPT-24Lumos OptiClear 24 plate, white polystyrene walls with a transparent COC bottom without MEA elctrodes, includes the Lumos lid, box of 5 plates

 

Other Accessories

SKUDescription
LUMOS-MEA-24Lumos MEA 24, 24-well MEA optical stimulation system with 4 LEDs per well, Blue/475, Green/530, Orange/612, Crimson/655. Control wavelength, duration, and intensity in each well. For use with the Maestro Pro or Edge system which is sold separately. 1 year warranty is included.
LUMOS-SA-24Lumos 24, 24-well MEA optical stimulation system with 4 LEDs per well, Blue/475, Green/530, Orange/612, Crimson/655. Control wavelength, duration, and intensity in each well. Includes laptop computer, AxIS software, and the Lumos stand for plate alignment and CO2 delivery. 1 year warranty is included.
MEA-CREATOR-128MEA Creator Kit, 128-channel adapter plate to allow interfacing with and acquisition from custom MEAs or devices. For use with the Maestro Pro, Edge, or Volt system which is sold separately. Does not include custom MEA design services. Interfacing with liquid handling platforms or other systems to automate MEA experiments. Includes functions for data acquisition and analysis.
CO2 REGModel 101-10M-CO2 (0-10bar) Carbon Dioxide Regulator with Adaptor

 

Service, Installation and Shipping

SKUDescription
INT-OSInstallation and Training, 2 days, Includes on-site installation and training covering hardware, software and applications. For Maestro systems. International.
INT-REInstallation and Training, 4 hours, Remote installation and training covering hardware, software and applications. International.
PAS384EDGEPerformance Assurance Service Plan – Maestro Edge. Additional 1 year in-factory service plan including all parts and labor. Does not include a preventive maintenance service.
PASOPTPerformance Assurance Service Plan – Lumos
additional 1 year in-factory service plan including all parts and labor.
PASPM384EDGEPerformance Assurance Service Plan with Preventive Maintenance – Maestro Edge. Additional 1 year in-factory service and preventive maintenance plan including all parts and labor. Includes one in-factory preventive maintenance service.
MAESTRO-SHPShipping for Maestro or TrayZ
CONS-SHPShipping for Axion Consumables
LUMOS-SHPShipping for Lumos

Insights Article: Micro Electrode Array Analyzers for Advanced Live Cell Analysis in South Africa 

Product Enquiry Handbook: Micro Electrode Array (MEA) Analyzers

Axion Biosystem’s Resource Library

Axion Neural Metric Tool

Axion Cardiac Metric Tool

Operation Manual – Maestro Edge

Product Enquiry

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