CytoView-Z delivers high-quality impedance results with a thin, transparent well bottom for culture visualization. Available in 96- and 384-well formats, CytoView-Z plates have a recording electrode embedded in the culture surface of each well, enabling non-invasive and label-free impedance measurements over days, weeks, or months. On-plate viewing windows aid cell visualization and imaging.
Key Features
Get more from every assay.
- Record high quality data: Recording electrode spans the entire well bottom surface to get the most information from your cells.
- Observe and image your cells with transparent plates: Compatible with light microscopy for daily culture monitoring.
- Assay multiplexing enriches impedance data: Complement your impedance assay with data from fluorescent or luminescent plate readers.
- Environmental control features: The evaporation-reducing lids and built-in humidity reservoirs help control your cells’ environment.
Overview
| CytoView-Z
The CytoView-Z plates combine robust impedance data collected with a transparent well bottom for cell visualization and assay multiplexing |
|||||||||||
| Plate | Cat No. | Wells | Electrode/ well |
Electrode layout* |
Bottom | Walls | Maestro Edge |
Maestro Pro |
Maestro Z |
Maestro ZHT |
Maestro Original |
|---|---|---|---|---|---|---|---|---|---|---|---|
| CytoView-Z 96 | Z96-IMP-96B |
96 |
1 Gold |  |
Transparent | Black | ● | ● | ● | ● | |
| CytoView-Z 384 | Z384-IMP-384B |
384 |
1 Gold |  |
Transparent | Black | ● | ● | |||
*Schematic of well illustrating the recording electrode (blue) and the ground (orange).
High quality impedance data
A number of different cell types perform well on the CytoView-Z plates, showing excellent attachment and proliferation across all wells and the exceptional signal quality Axion customers expect..
Cell visualization and assay multiplexing
The transparent well bottom (384- and 96-well) and on-plate viewing windows (96-well) offer additional assay flexibility including cell visualization and assay multiplexing. Bright field imaging enables correlation of cell culture health and connectivity with impedance results. Multiplex fluorescence- or luminescence-based assays with your impedance study to probe complementary endpoints.
Related Applications
- Antiviral Drug Studies – Evaluate the antiviral effects of test compounds by tracking real-time changes in cytopathic effects
- Barrier Function – Monitor cell barrier integrity using a TEER (transepithelial or transendothelial resistance) assay
- Cancer Spheroid – Model complex solid tumor biology to investigate the in vitro effects of immunotherapies and other anticancer agents
- CAR T Cell Killing – Quantify CAR T cell-mediated cytolysis of solid and liquid tumors
- Cell Migration and Invasion – Track cell migration and proliferation for advanced metastatic cancer or wound-healing studies
- Cell Proliferation – Reveal the kinetics of cellular proliferation and for improved insights of cell models
- Cell Signaling – Measure the dynamics of GPCR cell signaling over minutes to hours label free
- Cytotoxicity and Cell Viability – Evaluate cell viability and characterize the cytotoxic properties of compounds in acute and chronic exposure experiments
- Immuno-oncology – Evaluate killing kinetics of immune cells (e.g. CAR T or NK) at physiologically relevant effector cell to target cell ratios
- NK cell killing – Evaluate NK-mediated killing of cancer cells
- Viral Titer – Quantify the infectious virus in a sample by monitoring the cytopathic effects in real time
